模型信息
中文名称:SARS-CoV Toronto-2滴鼻感染雪貂模型
英文名称:SARS-CoV Toronto-2 intransally infection ferret model
类型:SARS-CoV感染动物模型
分级:NA
用途:用于SARS-CoV感染研究。
研制单位:阿拉巴马大学伯明翰分校@@http://southernresearch.org/
保存单位:阿拉巴马大学伯明翰分校@@http://southernresearch.org/
研究背景
暂无介绍
制备方法
Ferrets were divided randomly into four groups based upon SARS-CoV infection, mock infection, and challenge with both virus and mock inoculation. On 0 d.p.i., twentyfour ferrets (Group 1) were inoculated intranasally with serumfree medium only, and forty-two (Group 2) with SARS-CoV (103 TCID50/mL) diluted in medium. On 29 d.p.i., nine ferrets (Group 3) were inoculated with serum-free medium, and eighteen ferrets (Group 4) were challenged and inoculated with SARS-CoV (10^3 TCID50) diluted in medium. Prior to instillation of mock or virus inoculums, all ferrets were anesthetized,and 1 mL of the inoculum was administered intranasally by drop-wise delivery of 500 μL per nare.
评价验证
暂无介绍
生物安全性
暂无介绍
讨论与结论
轻度支气管炎
了解中析
实验室仪器
合作客户
